Divergent roles of nitrergic and prostanoid pathways in chronic joint inflammation

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Divergent roles of nitrergic and prostanoid pathways in chronic joint inflammation.

BACKGROUND Nitrergic and prostanoid pathways have both been implicated in inflammatory processes. OBJECTIVE To investigate their respective contributions in a rat model of chronic arthritis. METHODS Male Wistar rats (n = 4-6/group) received either an intra-articular injection of 2% carrageenan/4% kaolin (C/K) or intra- and periarticular injections of Freund's complete adjuvant (FCA; 10 mg/m...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 2004

ISSN: 0003-4967

DOI: 10.1136/ard.2003.017269